PHARMACOLOGICAL DIFFERENCES BETWEEN NATIVE HOMOMERIC TRANSIENT RECEPTOR POTENTIAL CANONICAL TYPE 4 CHANNELS AND HETEROMERIC TRANSIENT RECEPTOR POTENTIAL CANONICAL TYPE 1/4 CHANNELS IN LATERAL SEPTAL NEURONS

Given the unique expression patterns and revelations of its critical involvement in a host of neurological disorders, the TRPC1/4/5 subgroup has become an intense target of drug development, and some compounds are now in clinical trials.However, little is known about the exact subunit composition of this subfamily of TRPC channels in various native

We propose an effective scheme to enhance the efficiency of optical second-order sideband (OSS) via optomechanically induced absorption (OMIA) in sunflower horse halter a double-cavity optomechanical system.In this double-cavity optomechanical configuration, the optomechanical cavity is driven by a strong control field and a weak probe pulse, while

Abstract Background The aim of study was to observe the effect of increased lactate levels during high-intensity interval training (HIIT) on protein lactylation, identify the target protein, and investigate the regulatory effect of lactylation on the function of the protein.Methods C57B/L6 mice were divided into 3 groups: the control group, HIIT gr